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Recombinant Human Growth Hormone (CHO-expressed)

英文名：
Cas号：
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Growth Hormone (CHO-expressed) 是一种多肽激素，可刺激生长、细胞繁殖和细胞再生，能用于治疗儿童生长障碍。
Synonyms
rHuGH; Somatotropin; GH-N; GH1 ; 重组人生长激素 (CHO 细胞表达)
Species
Human

Source
CHO

Accession
P01241

Gene ID
2688

Molecular Weight
20-24 kDa

AA Sequence
FPTIPLSRLF DNASLRAHRL HQLAFDTYQE FEEAYIPKEQ KYSFLQNPQT SLCFSESIPT PSNREETQQK SNLELLRISL LLIQSWLEPV QFLRSVFANS LVYGASDSNV YDLLKDLEEG IQTLMGRLED GSPRTGQIFK QTYSKFDTNS HNDDALLKNY GLLYCFRKDM DKVETFLRIV QCRSVEGSCG F

Biological Activity
The ED50 is <0.5 ng/mL as measured by murine Balb/c 3T3 cells, corresponding to a specific activity of >2 × 106 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Growth Hormone (CHO-expressed) (rHuGH) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Human Growth Hormone (CHO-expressed) (rHuGH) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Recombinant Human Growth Hormone is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration, which can be used for the treatment of growth disorders in children[1]. Growth Hormone is a stress hormone that stimulates production of IGF-1 and raises the concentration of glucose and free fatty acids[2]. Growth Hormone exerts some of its effects by binding to receptors on target cells, where it activates the MAPK/ERK pathway[3].
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