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Recombinant 3C-like Proteinase, His
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性状 | Recombinant 3C-like Proteinase, His 在大肠杆菌中表达,N 端带有一个 His 标签,可介导病毒多聚蛋白的成熟和宿主蛋白的多次切割,以调节病毒的翻译和转录[1]。
Synonyms M Proteinase; 3CL Proteinase; 2019-nCoV 3C-like Proteinase Species Others Source E. coli Accession YP_009725301.1 Gene ID N/A Molecular Weight Approximately 33.0 kDa AA Sequence HHHHHHSGFR KMAFPSGKVE GCMVQVTCGT TTLNGLWLDD VVYCPRHVIC TSEDMLNPNY EDLLIRKSNH NFLVQAGNVQ LRVIGHSMQN CVLKLKVDTA NPKTPKYKFV RIQPGQTFSV LACYNGSPSG VYQCAMRPNF TIKGSFLNGS CGSVGFNIDY DCVSFCYMHH MELPTGVHAG TDLEGNFYGP FVDRQTAQAA GTDTTITVNV LAWLYAAVIN GDRWFLNRFT TTLNDFNLVA MKYNYEPLTQ DHVDILGPLS AQTGIAVLDM CASLKELLQN GMNGRTILGS ALLEDEFTPF DVVRQCSGVT FQ Biological Activity Data is not available. Appearance Solution. Formulation Supplied as a 0.2 μm filter solution of PBS, 1 mM EDTA, 10% Glycerol, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution N/A Storage & Stability Recombinant 3C-like Proteinase, His (r3C-like Proteinase, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Shipping with dry ice. Background The 3C protease has been regarded as a valid target due to its structural similarity among different picornaviruses and minimal sequence similarity with host proteins; therefore, the development of potent inhibitors against the 3C protease as an antiviral drug is ongoing. Duck hepatitis A virus (DHAV) belongs to the Picornavidea family and is a major threat to the poultry industry[1]. |
贮存 |
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