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Recombinant Human CD166, C-Fc (HEK293-expressed)
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| 性状 | Recombinant Human CD166, C-Fc (HEK293-expressed) 是一种由 HEK293 细胞表达的，C 末端有 Fc 片段的重组人 CD166。CD166，又称活化白细胞粘附分子 (ALCAM)，由多种细胞在包括癌症在内的多种组织中表达。
Synonyms rHuCD166, C-Fc; ALCAM; CD-166 ; 重组人 CD166，C-Fc (HEK293-expressed) Species Human Source HEK 293 Accession Q13740 Gene ID 214 Molecular Weight 110-125 kDa AA Sequence WYTVNSAYGD TIIIPCRLDV PQNLMFGKWK YEKPDGSPVF IAFRSSTKKS VQYDDVPEYK DRLNLSENYT LSISNARISD EKRFVCMLVT EDNVFEAPTI VKVFKQPSKP EIVSKALFLE TEQLKKLGDC ISEDSYPDGN ITWYRNGKVL HPLEGAVVII FKKEMDPVTQ LYTMTSTLEY KTTKADIQMP FTCSVTYYGP SGQKTIHSEQ AVFDIYYPTE QVTIQVLPPK NAIKEGDNIT LKCLGNGNPP PEEFLFYLPG QPEGIRSSNT YTLTDVRRNA TGDYKCSLID KKSMIASTAI TVHYLDLSLN PSGEVTRQIG DALPVSCTIS ASRNATVVWM KDNIRLRSSP SFSSLHYQDA GNYVCETALQ EVEGLKKRES LTLIVEGKPQ IKMTKKTDPS GLSKTIICHV EGFPKPAIQW TITGSGSVIN QTEESPYING RYYSKIIISP EENVTLTCTA ENQLERTVNS LNVSAISIPE HDEADEISDE NREKVNDQA Biological Activity Data is not available. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human CD166, C-Fc (HEK293-expressed) (rHuCD166, C-Fc) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human CD166, C-Fc (HEK293-expressed) (rHuCD166, C-Fc) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CD166, also known as activated leukocyte cell adhesion molecule (ALCAM), is a member of the immunoglobulin superfamily. It is detectable in a wide variety of cell types, including epithelial cells, lymphoid cells, myeloid cells, fibroblasts, neuronal cells, hepatocytes, and bone marrow cells. CD166 has been reported to be a marker for CSCs in colon cancer and prostate cancer, which indicates strong tumorigenicity[1]. |
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