14-3-3E (YWHAE)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 YWHAE antibody, 14-3-3E antibody, FLJ45465 antibody, FLJ53559 antibody, KCIP-1 antibody, MDCR antibody, MDS antibody, 14-3-3 protein epsilon antibody, antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】The 14-3-3 epsilon protein (14-3-3E) is one
of seven isoforms in the 14-3-3 protein family,
which consists of acidic proteins expressed at
high levels in neurons of the central nervous
system (1). It is an adaptor protein implicated in
the regulation of a large spectrum of both general
and specialized signaling pathways. 14-3-3E binds
to a large number of partners, usually by recognition
of a phosphoserine or phosphothreonine motif (2).
It also interacts with both insulin-like growth
factor I receptor (IGFIR) and insulin receptor
substrate I (IRS-1), suggesting its role in the
regulation of insulin sensitivity (3). 14-3-3E has
also been implicated in the pathogenesis of small cell
lung cancer (4).


Recommended Applications

WB, ICC, FC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:100 - 250
FC: 1:10 - 100
Species Reactivity

Human, Mouse, Rat

Specificity

A synthetic peptide corresponding to residues in human 14-3-3E was used as an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR3919
【用途】WB , ICC , FC
【抗原分子量】28kDa
贮存 Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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