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ADAM15
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113308-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | ADAM15 antibody, MDC15 antibody, Disintegrin and metalloproteinase domain-containing protein 15 antibody, Metargidin antibody |
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产品参数 | 【产品介绍】ADAM15 is a member of the ADAM (a
disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. ADAM15 contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, it specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that ADAM15 may function in cell-cell adhesion as well as in cellular signaling (1). Recommended Applications WB, IHC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:250 - 500 IP: 1:10 - 100 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on SW480 cell lysate using anti-ADAM15 RabMAb (cat. #5135-1). Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-ADAM15 RabMAb (cat.# 5135-1). Specificity A synthetic peptide corresponding to residues in the extracellular domain in human ADAM15 was used as an immunogen. |
性状 | 【反应特异性】Human
【用途】WB , IHC , IP 【抗原分子量】110 (pro-ADAM15) / 90 kDa (mature) |
贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |