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ACADM
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113305-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | ACADM antibody, ACAD1 antibody, FLJ18227 antibody, FLJ93013 antibody, FLJ99884 antibody, MCAD antibody, MCADH antibody, Medium-chain specific acyl-CoA dehydrogenase, mitochondrial antibody, antibody |
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产品参数 | 【产品介绍】Medium-chain specific acyl-CoA
dehydrogenase (ACADM) is a homotetramer enzyme of the mitochondrial flavoenzyme family that catalyzes the initial reaction in medium chain fatty acid beta-oxidation (1, 2). ACADM is specific for acyl chain lengths of 4 to 16 (3). It utilizes the electron transfer flavoprotein (ETF) as an electron acceptor that transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (3). Defects in the ACADM gene cause medium-chain acyl-CoA dehydrogenase deficiency (MCADD), a metabolic disorder characterized by fasting hypoglycemia (3). Mutation analysis can diagnose MCADD, which is currently screened in newborns, since its monogene may be modified by genetic variations (4). Recommended Applications WB, IHC, ICC, IP Applications and Recommended Dilution Factors WB: 1:10,000-50,000 IHC: 1:100 - 250 ICC: 1:100 - 250 IP: 1:10 - 100 Species Reactivity * Human, Mouse, Rat *Mouse cross reactivity tested by western blot and IHC Rat cross reactivity tested by western blot only Products Data Western blot analysis on (A) human heart, (B) fetal liver, (C) HeLa, (D) HepG2, and (E) K562 cell lysates using anti-ACADM RabMAb (cat. # 2833-1). Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-ACADM RabMAb (cat. #2833-1). Immunofluorescent staining of HeLa cells using anti-ACADM RabMAb (cat. #2833-1). Specificity A synthetic peptide corresponding to residues in human ACADM was used as an immunogen. |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR3708 【用途】WB , IHC , ICC , IP 【抗原分子量】43kDa |
贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |