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Akt1/PKBa Phospho (pS473)
英文名：Rabbit Monoclonal IgG
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113321-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | RAC-PK-alpha, Protein kinase B, PKB, C-AKT |
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| 产品参数 | 【产品介绍】Akt1/PKBa is a Ser/Thr protein kinase
whose kinase activity plays a key role in various cellular functions, including apoptosis, glycogen synthesis, a n d cell growth . Akt1/PKBa is activated by various growth a n d survival fact o r s (1). Phosph o r ylation on Thr308, Ser473 a n d Tyr474 is required f o r full activity. Akt1/PKBa inhibits apoptosis by phosph o r ylating a n d inactivating several targets, including caspase-9 (2). Akt1/PKBa regulates glycogen synthesis by phosph o r ylating a n d inactivating glycogen synthase kinase-3a a n d b (3,4). Three mammalian Akt1/PKBa isof o r ms have been identified. WB: 1:5000 - 10,000 IHC: 1:100 250 ICC: 1:100 250 A. Immunohistochemical analysis of untreated cervical carcinoma using anti-Phospho-Akt1 (pS473) RabMAb (cat. # 2118-1). B. Immunohistochemical analysis of Phosphatase- treated cervical carcinoma using anti-Phospho-Akt1 (pS473) RabMAb (cat. # 2118-1). C. Western blot analysis on 3T3 cell lysates using anti-Phospho-Akt1 (pS473) RabMAb (cat. #2118-1), 1:10,000 dilution. Cells were either (A) untreated o r (B) treated with PDGF. |
| 性状 | 【反应特异性】Human , Mouse
【克隆 ID】EP2109Y 【用途】WB , IHC , ICC 【抗原分子量】60 kDa |
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