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Alpha-Actin (Smooth Muscle) (ACTA2)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113325-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | ACTA2 antibody, AAT6 antibody, ACTSA antibody, Actin, aortic smooth muscle antibody, Alpha-actin-2 antibody, Cell growth-inhibiting gene 46 protein antibody |
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| 产品参数 | 【产品介绍】Actins are highly conserved
proteins ubiquitously expressed in all eukaryotic cells. They comprise, along with microtubules, a major component of the cytoskeleton. Actin has been found to be expressed in at least six isomeric forms. It is expressed in heart and skeletal striated muscle tissue, and in certain smooth muscle tissues, regulating contractile potentials for these cells. It is also expressed in the cytoplasm of non-muscle cells, functioning to control cell structure and motility (1). Polymerization of globular actin (G-actin) leads to a structural filament (F-actin), whose formation requires the Arp2/3 complex (2). It has been reported that actin is hyperphosphorylated in primary breast tumors (3). It has also been shown that actin dysfunction leads to certain types of heart failure (4). Smooth muscle alpha actin is of further interest because it is one of a few genes whose expression is relatively restricted to vascular smooth muscle cells. Furthermore, expression of smooth muscle alpha actin is regulated by hormones and cell proliferation, and is altered by pathological conditions including oncogenic transformation and atherosclerosis (5). Recommended Applications IHC, ICC, FC Applications and Recommended Dilution Factors IHC: 1:1000 - 2500 ICC: 1:250 - 500 FC: 1:10 - 100 Species Reactivity Human, Mouse, Rat Products Data Immunohistochemical analysis of paraffin-embedded human heart tissue using anti-Alpha-Actin (Smooth Muscle) RabMAb (cat.# 5264-1). Immunohistochemical analysis of paraffin-embedded human ovary tissue using anti-Alpha-Actin (Smooth Muscle) RabMAb (cat.# 5264-1). Specificity A synthetic peptide corresponding to residues on the N-terminus in human Alpha-Actin (Smooth Muscle) was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR5368 【用途】IHC , ICC , FC 【抗原分子量】42kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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