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Akt1/PKBa (C-term)
英文名:Rabbit Monoclonal IgG
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113318-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | RAC-PK-alpha, Protein kinase B, PKB, C-AKT |
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产品参数 | 【产品介绍】Akt1/PKBa is a Ser/Thr protein kinase
whose kinase activity plays a key role in various cellular functions, including apoptosis, glycogen synthesis, a n d cell growth . Akt1/PKBa is activated by various growth a n d survival fact o r s (1). Phosph o r ylation on Thr308, Ser473 a n d Tyr474 is required f o r full activity. Akt1/PKBa inhibits apoptosis by phosph o r ylating a n d inactivating several targets, including caspase-9 (2). Akt1/PKBa regulates glycogen synthesis by phosph o r ylating a n d inactivating glycogen synthase kinase-3a a n d b (3,4). Three mammalian Akt1/PKBa isof o r ms have been identified. WB: 1:5,000-10,000 IHC: 1:100 ICC: 1:100-1:250 Flow Cytometry: 1:20 IP: 1:100 A. Western blot analysis on MCF-7 cell lysate using anti- Akt1/PKBa (C-term) RabMAb (cat. #1081-1); dilution 1:10,000. B. Immunohistochemical analysis of paraffin-embedded prostate carcinoma using anti-Akt1/PKBa (C-term) RabMAb (cat. #1081-1). |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】Y89 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】59 kDa |
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