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B7-H2 (ICOSLG)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113351-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | ICOSLG antibody, B7-H2 antibody, B7H2 antibody, B7RP-1 antibody, B7RP1 antibody, CD275 antibody, GL50 antibody, ICOS-L antibody, ICOSL antibody, KIAA0653 antibody, LICOS antibody, ICOS ligand antibody, B7-like protein Gl50 antibody, B7-related protein 1 a |
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| 产品参数 | 【产品介绍】B7-H2, or Inducible costimulator ligand
(ICOSL), is a member of the Ig superfamily and belongs to the B7 family of costimulatory molecules. It specifically binds to ICOS, but not to other T cell costimulatory molecules such as CD28 and CTLA-4. B7-H2-ICOS interaction appears to be very important in the expansion of activated T cells and late-phase immune responses (1). B7-H2 enhances the proliferation of both CD4 and CD8 T cells, the secretion of Th1- and/or Th2-type cytokines, and the expression of CD154 (CD40 ligand) on T cells (2). It is expressed constitutively on B lymphocytes and at low levels on monocytes (3). Furthermore, B7-H2-ICOS interaction induces IL-10 production, which plays an important role in reducing immune responses (4). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:50 - 100 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) HL-60, (B) HuT78, (C) HUVEC treated with TNF-alpha, and (D) HUVEC cell lysates using anti-B7-H2 RabMAb (cat. #5329-1). Specificity A synthetic peptide corresponding to residues in the intracellular domain of human B7-H2 was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR6071 【用途】WB , ICC 【抗原分子量】63 - 72kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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