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Bad (N-term)
英文名:Rabbit Monoclonal IgG
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113353-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | BAD, Bcl-2-binding component 6, Bcl-XL/Bcl-2-associated death promoter, Bcl-2-like 8 protein |
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产品参数 | 【产品介绍】Bad is a pro-apoptotic member of the
Bcl-2 family. Bad will bind preferentially Bcl-xL over Bcl-2 through its partial (9-16 a.a) BH3 domain. Additionally, Bad can reverse the death repress o r activity of Bcl-xL but not of Bcl-2. Upon dephosph o r ylation, activated Bad translocates to the mitochondria a n d displace Bcl-2 from tBid sequestration to initiate mitochondrial dysfunction. The switching on/off of its phosph o r ylation by growth/survival fact o r s regulates Bad activity. WB: 1:2,000-5,000 IHC: 1:100-250 ICC: 1:250-500 Flow Cytometry: 1:50 IP: 1:100 A.Western blot analysis on Hela cell lysate using anti-Bad (N-term) RabMAb (cat. # 1541-1), dilution 1:5,000. B. Immunohistochemical staining of paraffin-embedded human lymphoma using anti-Bad (N-term) RabMAb (cat. # 1541-1) C. Immunohistochemical staining of paraffin-embedded human lymphoma using a anti-Bad (N-term) RabMAb (cat. # 1541-1) |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】Y208 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】23 kDa |
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