Bad (N-term)

英文名:Rabbit Monoclonal IgG
Cas号:
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别 名 BAD, Bcl-2-binding component 6, Bcl-XL/Bcl-2-associated death promoter, Bcl-2-like 8 protein
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Bad is a pro-apoptotic member of the
Bcl-2 family. Bad will bind preferentially Bcl-xL over
Bcl-2 through its partial (9-16 a.a) BH3
domain. Additionally, Bad can reverse the death repress
o r activity of Bcl-xL but not of Bcl-2. Upon
dephosph o r ylation, activated Bad translocates to
the mitochondria a n d displace Bcl-2 from
tBid sequestration to initiate mitochondrial
dysfunction. The switching on/off of its phosph o r
ylation by growth/survival fact o r s regulates Bad
activity.


WB: 1:2,000-5,000
IHC: 1:100-250
ICC: 1:250-500
Flow Cytometry: 1:50
IP: 1:100


A.Western blot analysis on Hela cell lysate using
anti-Bad (N-term) RabMAb (cat. # 1541-1), dilution 1:5,000.

B. Immunohistochemical staining of paraffin-embedded
human lymphoma using anti-Bad (N-term) RabMAb (cat. # 1541-1)

C. Immunohistochemical staining of paraffin-embedded
human lymphoma using a anti-Bad (N-term) RabMAb
(cat. # 1541-1)

性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】Y208
【用途】WB , IHC , ICC , FC , IP
【抗原分子量】23 kDa
贮存
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