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Bag-2 (BAG2)
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113355-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | BAG2 antibody, BAG-2 antibody, KIAA0576 antibody, MGC149462 antibody, dJ417I1.2 antibody, BAG family molecular chaperone regulator 2 antibody, Bcl-2-associated athanogene 2 antibody |
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产品参数 | 【产品介绍】BAG-2 is a member of a family of
BAG-related proteins (BAG-2, BAG-3, BAG-4, BAG-5). BAG-family proteins may play a role in providing opportunities for specification and diversification of Heat Shock Protein (Hsp70) chaperone functions. Hsp70 family molecular chaperones play critical roles in protein folding and trafficking in all eukaryotic cells. BAG-1 binds the ATPase domains of Hsp70 and Hsc70, modulating their chaperone activity and functioning as a competitive antagonist of the co-chaperone Hip. BAG-2 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner (1). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1000 - 2000 ICC: 1:100 - 250 Species Reactivity * Human, Mouse, Rat *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on (A) Jurkat (B) HeLa and (C) A549 cell lysate using anti-Bag2 RabMAb (cat. # 2622-1), dilution 1:2000. B. Immunofluorescent staining of HeLa cells using anti-BAG2 RabMAb (cat. #2622-1). Specificity A synthetic peptide corresponding to residues in the C-terminus of human Bag-2 was used as immunogen. |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR3568 【用途】WB , ICC 【抗原分子量】23kDa |
贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |