Bcl-x Rabbit Antibody

英文名:Rabbit Monoclonal IgG
Cas号:
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别 名 Bcl-2-like 1 protein
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Bcl-x, a member of the Bcl-2 protein
family, inhibits cell death, o r apoptosis (1). Bcl-x
is expressed as two isomeric f o r ms, Bcl-xL a n d
Bcl-xS, a n d is typically present in the cytosol
in association with the mitochondrial membrane. Bcl-xL
f o r ms heterodimers with various proteins, including
Bax, Bak a n d Bcl-2 (2). It has been found that eterodimerization with Bax does not seem to be required
f o r anti-apoptotic activity (3). Since Bcl-xL can
f o r m an ion channel in synthetic lipid membranes,
there is a strong possibility that this property plays
a role in heterodimerization-independent cell survival
(4). The Bcl-X(S) isof o r m promotes apoptosis.


WB: 1:1,000
IHC: 1:50 - 1:100
ICC: 1:100
Flow Cytometry: 1:50
IP: 1:10


A. Western blot analysis of K562 cell lysate
using anti-Bcl-x RabMAb (catalog #1018-1), 1:1,000 dilution.

B. Immunohistochemical analysis of human
paraffin-embedded prostate carcinoma tissue using
anti-Bcl-x RabMAb (catalog #1018-1).

C. Flow cytometric analysis of permeabilized K562
cells using anti-Bcl-x RabMAb (red) (catalog #1018-1)
o r a Rabbit IgG (negative) (green).
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】E18
【用途】WB , IHC , ICC , FC , IP
【抗原分子量】26 (Bcl-xL) / 19 (Bcl-xS) kDa
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