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Bcl-2 Rabbit Antibody
英文名：Rabbit Monoclonal IgG
Cas号：
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113360-100ul | 现货 | 0 | ￥0 | 请登录 |
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| 产品参数 | 【产品介绍】The Bcl-2 family of proteins regulate
apoptosis by controlling mitochondrial permeability a n d release of cytochrome c. Bcl-2 is an anti-apoptotic protein that resides in the outer mitochondrial wall a n d inhibits release of cytochrome c (1). Over-expression of Bcl-2 has been shown to promote cell survival by suppressing apoptosis. It has been documented that bcl-2 becomes deregulated in tum o r cells as a result of translocation into the immunoglobulin heavy-chain locus a n d is theref o r e activated in B cell malignancies (2). It has also been shown that post-translational modification of Bcl-2, phosph o r ylation at serine 70, may be required to render its full a n d / o r enhanced anti-apoptotic effect (3, 4). WB: 1:500 IHC: 1:100-1:200 ICC: 1:00 Flow Cytometry: 1:200 IP: 1:50 A. Western blot analysis of Jurkat cell lysate using anti-Bcl-2 RabMab (Cat#1017-1), 1:1,000 dilution. B. Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-BCL-2 Rab Mab (Cat#1017-1). C. Flow cytometric analysis of permeabilized Jurkat cells using anti-Bcl-2 RabMAb (red)(catalog #1017-1) o r a rabbit IgG (negative) (green). |
| 性状 | 【反应特异性】Human , Mouse
【克隆 ID】E17 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】26 kDa |
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