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Bim
英文名:Rabbit Monoclonal IgG
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113372-100ul | 现货 | 0 | ¥0 | 请登录 |
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产品参数 | 【产品介绍】Bim, Bcl-2 interacting mediat o r of cell
death, is a pro-apoptotic protein belonging to the BH3-only group of Bcl-2 family members (1). Bim promotes apoptosis by binding to a n d inhibiting the activity of anti-apoptotic Bcl-2 family members, inducing the release of cytochrome c from mitochondria (2). Bim is sequestered in an inactive conf o r mation through binding to the microtubule-associated dynein mot o r complex. Certain apoptotic stimuli release Bim from microtubules, allowing inhibit o r y binding to anti-apoptotic Bcl-2 family members a n d subsequent iniation of apoptosis (3,4). WB: 1:500 IHC: 1:100 ICC: 1:100 IP: 1:40 A. Western blot analysis on A431 cell lysate using anti-Bim RabMAb (cat. #1036-1), dilution 1:500. B. Immunohistochemical analysis of paraffin-embedded breast carcinoma using anti-Bim RabMAb (cat. #1036-1). |
性状 | 【反应特异性】Human
【克隆 ID】Y36 【用途】WB , IHC , ICC , IP 【抗原分子量】22 kDa |
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