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B-Raf Phospho (pS729) (BRAF)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113376-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | BRAF antibody, B-RAF1 antibody, BRAF1 antibody, FLJ95109 antibody, MGC126806 antibody, MGC138284 antibody, NS7 antibody, RAFB1 antibody, Serine/threonine-protein kinase B-raf antibody, Proto-oncogene B-Raf antibody, p94 antibody, v-Raf murine sarcoma vira |
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| 产品参数 | 【产品介绍】B-Raf, also know as c-Rmil, is
a Serine/Threonine protein kinase member of the Raf family which includes Raf-1 and A-Raf. B-Raf is involved in the transduction of mitogenic signals from the cell membrane to the nucleus (1). Composed of three conserved region (CR1, CR2, CR3) B-Raf is expressed primarily in the brain and in the nervous system (2). It has been observed that MAPK is activated by B-Raf in response to nerve growth factor (3). More than 60% of malignant melanomas were found to contain a specific mutation, B-Raf (V599E) the product of which possesses constitutive kinase activity (4). Mutations in B-Raf have also been identified in lung cancer and non-Hodgkin lymphoma. Recommended Applications WB, IHC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on PC-12 cell lysates using anti-Phospho-B-Raf (pS729) RabMAb (cat. #5170-1). Cells were either (A) untreated (B) treated with Lambda Phosphatase. Specificity A phospho specific peptide corresponding to residues surrounding serine 729 of human B-Raf was used as an immunogen. This antibody detects B-Raf phosphorylated on serine 729. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR2207 【用途】WB , IHC 【抗原分子量】94kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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