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BLNK Rabbit Antibody
英文名：Rabbit Monoclonal IgG
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113373-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | Cytoplasmic adapter protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65 |
| Cas号 | |
| M D L | |
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| 产品参数 | 【产品介绍】B-cell linker protein (BLNK, also known
as SLP65, BASH, a n d BCA) is a B cell adapt o r that plays an imp o r tant role in B cell development a n d in BCR-signal transduction. Since BLNK does not encode any intrinsic enzymatic activity, its function is to serve as a scaffold f o r assembling macromolecular complexes which includes enzymes (PLC gamma, Vav a n d Btk) a n d additional linker proteins (Grb2 a n d Nck) (1-3) . In addition, BLNK binds Btk a n d is required f o r activation of the transcription fact o r NF-κB. Tyrosine phosph o r ylation of BLNK by Syk provides specific docking sites f o r these SH2-containing effect o r proteins which in turn permits phosph o r ylation a n d / o r activation of their respective signaling pathways. WB: 1:500 IHC: 1:50 IP: 1:20 A. Western blot analysis on Raji cell lysate using anti-BLNK (RabMAb (cat. #1597-1), 1:500 dilution. B. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-BLNK RabMAb (cat. # 1597-1). |
| 性状 | 【反应特异性】Human , Mouse
【克隆 ID】Y491 【用途】WB , IHC , IP 【抗原分子量】68/70 kDa |
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