CHD5

英文名:Rabbit Monoclonal Antibody
Cas号:
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货号 规格 货期 库存 价格 会员价 订购
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别 名 CHD5 antibody, DKFZp434N231 antibody, KIAA0444 antibody, Chromodomain-helicase-DNA-binding protein 5 antibody, ATP-dependent helicase CHD5 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】CHD5 belongs to a group of SWI/SNF
proteins called CHD proteins, which contain a
SWI/SNF-like helicase/ATPase domain, as well as
a DNA-binding domain and a chromodomain that
directly modifies chromatin structure. It is most
homologous to CHD3 and CHD4, which are proteins that
are part of the nucleosome remodeling and
histone deacetylation (NuRD) complex. CHD5 is
preferentially expressed in total brain, fetal brain,
and cerebellum. It is also moderately expressed in
the adrenal gland, but expression is undetectable in
almost all other tissues examined. CHD5 maps within a
small region of deletion on 1p36.3 in human
neuroblastomas, a common pediatric tumor. It has
been suggested that this protein may play a role in
the development of the nervous system, and it may also
play a role in the pathogenesis of neural tumors (1).


Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:50,000 - 200,000
ICC: 1:250 - 500
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.


Products Data

Western blot analysis on (A) human adrenal gland
and (B) SH-SY5Y cell lysates using anti-CHD5
RabMAb (cat. #5212-1).

Immunofluorescent staining of SH-SY5Y cells using
anti-CHD5 RabMAb (cat. #5212-1).

Specificity

A synthetic peptide corresponding to residues in human
CHD5 was used as an immunogen. The antibody is predicted
to cross-react with CHD3.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6053
【用途】WB , ICC
【抗原分子量】260kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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