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CSN7A (COPS7A)
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113471-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | COPS7A antibody, CSN7A antibody, MGC110877 antibody, COP9 signalosome complex subunit 7a antibody, Dermal papilla-derived protein 10 antibody, JAB1-containing signalosome subunit 7a antibody |
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产品参数 | 【产品介绍】CSN7A is a component of the COP9
signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (1). CSN7A and PMF-1 bind to each other, as well as compete with each other for binding to Nrf-2. This competition for Nrf-2 binding and interaction with each other is implicated in the regulation of SSAT transcription (2). Recommended Applications WB Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 Species Reactivity * Human, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) HeLa, (B) JAR, (C) fetal muscle, (D) human brain, (E) human heart, and (F) human kidney lysates using anti-CSN7A RabMAb (cat. #5213-1). Specificity A synthetic peptide corresponding to residues in human CSN7A was used as an immunogen. |
性状 | 【反应特异性】Human , Rat
【克隆 ID】EPR6463 【用途】WB 【抗原分子量】30kDa |
贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |