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Cyclin E1 Phospho (pT77) (CCNE1)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113475-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | CCNE1 antibody, CCNE antibody, G1/S-specific cyclin-E1 antibody, antibody |
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| 产品参数 | 【产品介绍】Cyclin E1 is a member of the cyclin E
family that can associate with and activate cyclin-dependent kinase Cdk2. Expression of cyclin E1 is essential for the control of the cell cycle at the late G1 and early S phase (1). The cyclin E/Cdk2 complex plays an essential and limiting role in the transition between G1 and S phase as well as the initiation of DNA replication (2) Ubiquination by the Cul-3 pathway and by Fbw7 regulates cyclin E1 levels and is critically important in normal cells. Abnormally high levels of cyclin E expression have frequently been observed in human cancers (3). Moreover, high cyclin E1 levels correlate with increased tumor aggression and poor prognosis (4). Recommended Applications WB, IHC, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 ICC: 1:250 - 500 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on JAR cell lysates using anti-Phospho-Cyclin E1 (pT77) RabMAb (cat. #5105-1). Cells were either (A) untreated or (B) treated with Lambda Phosphatase. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Phospho-Cyclin E1 (pT77) RabMAb (cat. #5105-1). Specificity A phospho specific peptide corresponding to residues surrounding Threonine 77 of human Cyclin E1 was used as an immunogen. This antibody only detects Cyclin E1 phosphorylated at Threonine 77. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR2242(2) 【用途】WB , IHC , ICC 【抗原分子量】50kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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