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CrkL Rabbit Antibody
英文名:Rabbit Monoclonal IgG
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113469-100ul | 现货 | 0 | ¥0 | 请登录 |
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产品参数 | 【产品介绍】CrkL (Crk-like), a 36kDa protein
predominantly expressed in hematopoietic cell lines, is a member of the Crk adapter protein family. Lacking any intrinsic enzymatic activity, CrkL is composed of one SH2 domain a n d two SH3 domains (1). The SH2 domain of CrkL as been shown to interact with c-Cbl, Cas, Hef-1 a n d Paxillin (2); while the N-terminal SH3 can bind to c-ABL, Sos1 a n d C3G (3). Additionally, the phosph o r ylated f o r m of CrkL (pY207) binds to BCR-ABL oncogene in chronic myelogenous leukemia cells (4). WB: 1:1,000 IHC: 1:50-100 ICC: 1:50-100 A. Western blot analysis on K562 cell lysate using anti-CrkL RabMAb (cat. # 1537-1), dilution 1:1,000. B. Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-CrkL RabMAb (cat. # 1537-1). |
性状 | 【反应特异性】Human
【克隆 ID】Y243 【用途】WB , IHC , ICC 【抗原分子量】39 kDa |
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