DCTN3

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 DCTN3 antibody, DCTN-22 antibody, DCTN22 antibody, MGC111190 antibody, Dynactin subunit 3 antibody, Dynactin complex subunit 22 kDa subunit antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】DCTN3 is the smallest subunit of dynactin,
a macromolecular complex consisting of 10 subunits
ranging in size from 22 to 150 kDa. Dynactin binds to
both microtubules and cytoplasmic dynein. It is involved
in a diverse array of cellular functions,
including ER-to-Golgi transport, the centripetal movement
of lysosomes and endosomes, spindle formation,
cytokinesis, chromosome movement, nuclear positioning,
and axonogenesis. This subunit, like most other
dynactin subunits, exists only as a part of the
dynactin complex. DCTN3 is primarily an
alpha-helical protein with very little coiled coil,
and binds directly to the largest subunit (p150) of
dynactin (1).


Recommended Applications

WB, IHC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:100 - 250
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) 293T, (B) mouse muscle,
(C) HeLa, (D) BxPC-3, (E) SH-SY5Y, and (F) rat
muscle lysates using anti-DCTN3 RabMAb (cat. #5137-1).


Immunohistochemical analysis of paraffin-embedded
human breast tissue using anti-DCTN3 RabMAb (cat.# 5137-1).

Note: Dilute primary antibody in 1% BSA.

Specificity

A synthetic peptide corresponding to residues in human
DCTN3 was used as an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR5097
【用途】WB , IHC
【抗原分子量】22kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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