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| 生化科研试剂 >> 抗体产品 >> 一抗 |
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eEF-2K
Rabbit Monoclonal IgG |
| 别 名： |
eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent eukaryotic elongation fact o r 2 kinase |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177740 |
eEF-2K |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human , Mouse , Rat
【克隆 ID】EP724Y
【用途】WB , IP
【抗原分子量】95 kDa
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| 质量标准： |
【产品介绍】Eukaryotic elongation fact o r -2
kinase (eEF-2k) previously known as Ca2+/
calmodulin-dependent protein kinase III, is an
abundant cytoplasmic protein highly specific
f o r elongation fact o r -2 (eEf-2) (1). Phosph o r
ylation of eEF-2 by eEF-2 kinase on specific
threonine residues results in the inactivation of eEF-2
a n d in termination of mRNA translation (2). The
activity of eEF2 kinase is not only dependent upon
Ca2+ ions, calmodulin (CaM) a n d insulin, but is
also regulated both negatively a n d positively by phosph
o r ylation by different protein kinases (AMPK, S6K1,
p90 RSK) (3-4). There is also evidence that eEF-2 phosph
o r ylation is involved in the regulation of cell
cycle progression, cellular differentiation, oogensis
a n d malignant tum o r s (5-6).
WB: 1: 50,000
IP: 1:20
A. Western blot analysis on HeLa (lane A) a n d Jurkat
(lane B) using anti- eEF-2K RabMAb (cat. # 1718-1),
dilution 1:50,000
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