本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
EGFR (C-term)
英文名：Rabbit Monoclonal IgG
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113539-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | Recept o r tyrosine-protein kinase ErbB-1 |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | 【产品介绍】Epidermal growth fact o r recept o r (EGFR) is
a 170 kDa transmembrane glycoprotein recept o r tyrosine kinase that, activated by epidermal growth fact o r (EGF), affects cell growth a n d differentiation (1). Binding of EGF o r TGF alpha to EGFR activates tyrosine kinase activity of the recept o r (2). The carboxy terminal tyrosine residues on EGFR, Tyr 1068, Tyr 1148, a n d Tyr 1173, are the maj o r sites of autophosph o r ylation, which occurs as a result of EGF binding (3). Once activated, EGFR phosphotyrosines Y-1068 a n d Y-1173 mediate the binding of Grb2 to the EGFR. Another autophosph o r ylation site, Tyr 1086, is situated within the cytoplasmic domain, a n d is phosph o r ylated to a higher extent by c-Src than by EGFR (4). WB: 1:10,000 ICC: 1:50 Flow Cytometry: 1:10 IP: 1:30 A. Western blot analysis on A431 cell lysate using anti-EGFR (C-term) RabMAb (cat. #2235-1); dilution 1:10,000. B. Immunoflu o r escent staining of A431 cells using anti-EGFR (C-term) RabMAb (cat. #2235-1). |
| 性状 | 【反应特异性】Human
【克隆 ID】E235 【用途】WB , ICC , FC , IP 【抗原分子量】170 kDa |
| 贮存 |
沪公网安备 31012002003054号