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EGFR
英文名：Rabbit Monoclonal IgG
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113538-100ul | 现货 | 0 | ￥0 |
| 别 名 | Recept o r tyrosine-protein kinase ErbB-1 |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | 【产品介绍】Epidermal growth fact o r recept o r (EGFR) is
a 170 kDa transmembrane glycoprotein recept o r tyrosine kinase that, activated by epidermal growth fact o r (EGF), affects cell growth a n d differentiation (1). Binding of EGF o r TGF alpha to EGFR activates tyrosine kinase activity of the recept o r (2). Phosph o r ylation of Tyr 992, Tyr 1068 a n d Tyr 1086 is required f o r conf o r mational change in the C-terminal of EGFR (3). Autophosph o r ylation of Tyr 992 c r e a t e s a binding site f o r the phospholipase C-gamma (PLC-gamma) SH2 domain, inducing downstream signaling (4). WB: 1:5,000 IHC: 1:10-25 ICC: 1:10 IP: 1:10 A. Western blot analysis of A431 cell lysate using anti EGFR RabMab, (cat# 1114 -1) dilution 1:5,000 B. Immunohistochemical anlysis of human cervical carcinoma using anti EGFR RabMab, cat# 1114 -1 C. Immunoflu o r escent staining of A431 cells using anti EGFR RabMab, cat# 1114 -1 |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】E114 【用途】WB , IHC , ICC , IP 【抗原分子量】170-180 kDa |
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