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FBNRG3 DyLight® 488
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113579-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | NRG3 antibody, HRG3 antibody, pro-NRG3 antibody, Neuregulin-3 antibody, antibody |
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产品参数 | 【产品介绍】FBNRG3, or Neuregulin 3, is a member of
the neuregulin family. This family consists of ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. FBNRG3 has been shown to activate tyrosine phosphorylation of its cognate receptor, ERBB4, and it is thought to influence neuroblast proliferation, migration and differentiation by signaling through ERBB4. FBNRG3 also promotes mammary differentiation during embryogenesis. Studies have implicated this protein in schizophrenia and schizoaffective disorder (1). Recommended Applications FC Applications and Recommended Dilution Factors FC: 1:100 Species Reactivity Human Products Data Flow cytometric analysis of C6 cells using FBNRG3 RabMAb (DyLight® 488 conjugate, cat.# 4571-1) (red) compared to a nonspecific negative control antibody (green). Specificity A synthetic peptide corresponding to residues in the cytoplasmic domain of human FBNRG3 was used as an immunogen. |
性状 | 【反应特异性】Human
【克隆 ID】EPR4148 【用途】FC 【抗原分子量】56kDa |
贮存 | Storage Condition and Buffer Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt. |