FBNRG3 DyLight® 488

英文名:Rabbit Monoclonal Antibody
Cas号:
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货号 规格 货期 库存 价格 会员价 订购
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别 名 NRG3 antibody, HRG3 antibody, pro-NRG3 antibody, Neuregulin-3 antibody, antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】FBNRG3, or Neuregulin 3, is a member of
the neuregulin family. This family consists of ligands
for the transmembrane tyrosine kinase receptors ERBB3
and ERBB4 - members of the epidermal growth factor
receptor family. Ligand binding activates
intracellular signaling cascades and the induction
of cellular responses including proliferation,
migration, differentiation, and survival or
apoptosis. FBNRG3 has been shown to activate
tyrosine phosphorylation of its cognate receptor, ERBB4,
and it is thought to influence neuroblast
proliferation, migration and differentiation by
signaling through ERBB4. FBNRG3 also promotes
mammary differentiation during embryogenesis. Studies
have implicated this protein in schizophrenia
and schizoaffective disorder (1).


Recommended Applications

FC
Applications and Recommended Dilution Factors

FC: 1:100
Species Reactivity

Human

Products Data

Flow cytometric analysis of C6 cells using FBNRG3
RabMAb (DyLight® 488 conjugate, cat.# 4571-1)
(red) compared to a nonspecific negative control
antibody (green).

Specificity

A synthetic peptide corresponding to residues in
the cytoplasmic domain of human FBNRG3 was used as
an immunogen.
性状 【反应特异性】Human
【克隆 ID】EPR4148
【用途】FC
【抗原分子量】56kDa
贮存 Storage Condition and Buffer Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt.
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