【产品介绍】FOXE1 belongs to the forkhead family
of transcription factors, which is characterized by
a distinct forkhead domain. It functions as a
thyroid transcription factor which likely plays a
crucial role in thyroid morphogenesis. Mutations in
FOXE1 are associated with congenital hypothyroidism
and cleft palate with thyroid dysgenesis. It may also be
a candidate protein for squamous cell epithelioma
and hereditary sensory neuropathy type I (1).
Recommended Applications
WB, IHC, ICC, IP
Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:100 - 250
IP: 1:10 - 100
Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data
Western blot analysis on (A) human testis, (B) Caco-2,
(C) HeLa, (D) TT and (E) BxPC-3 lysates using
anti-FOXE1 RabMAb (cat. #5343-1). Immunohistochemical analysis of paraffin-embedded human
lung tissue using anti-FOXE1 RabMAb (cat.# 5343-1). Immunohistochemical analysis of paraffin-embedded
human muscle tissue using anti-FOXE1 RabMAb (cat.# 5343-1). Specificity A synthetic peptide corresponding to residues in human
FOXE1 was used as an immunogen. |
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