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Fra-2 (FOSL2)
英文名：Rabbit Monoclonal Antibody
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| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113604-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | FOSL2 antibody, FLJ23306 antibody, FRA2 antibody, Fos-related antigen 2 antibody, antibody |
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| 产品参数 | 【产品介绍】Fra-2, one of the Fos-related antigens,
is promptly expressed after the growth stimulation of fibroblasts, but its induction peak is later than that of c-Fos (1). Fra-2 belongs to the activator protein 1 family of transcription factors, and it regulates the production of extracellular matrix in systemic sclerosis (SSc). It has been demonstrated that Fra-2 is overexpressed in SSc and acts as a novel downstream mediator of the profibrotic effects of TGFβ and PDGF. It might be an interesting novel candidate for molecular-targeted therapies for SSc (2). Recommended Applications WB, IP, FC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IP: 1:10 - 100 FC: 1:100 - 500 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) MCF-7, (B) F9, (C) PC-12, (D) NCCIT, and (E) 293T cell lysates using anti-Fra-2 RabMAb (cat. #5365-1). Flow cytometric analysis of permeabilized 293T cells using anti-Fra-2 RabMAb (red) (catalog # 5365-1) or a rabbit IgG (negative) (green). Specificity A synthetic peptide corresponding to residues near the C-terminus of human Fra-2 was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR4713(2) 【用途】WB , FC , IP 【抗原分子量】46kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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