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Gab1 Phospho (pY627)
英文名:Rabbit Monoclonal IgG
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113614-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | GRB2-associated binder 1 |
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产品参数 | 【产品介绍】Gab1 (Grb2-associated binder-1) is an adapt
o r protein that serves to activate numerous intracellular signaling pathways via its interaction with recept o r tyrosine kinases (RTKs). Gab1 is a substrate of various RTKs, including EGFR, insulin recept o r , cytokine recept o r s, a n d B cell antigen recept o r s; a n d it acts as a docking protein f o r several SH2-containing proteins (1-3). Tyrosine-phosph o r ylated Gab1 may recruit cytosolic signaling proteins to the cellular membrane, where they can act on membrane-bound targets as well as activate downstream pathways (4). WB: 1:1000 IHC: 1:250 IP: 1:50 A. Western blot analysis of immunoprecipitation pellets using (A) serum starved 293 cell lysate o r (B) serum starved 293 cell lysate + insulin in the presence of anti-Phospho-Gab1 (pY627) RabMAb (catalog #1128-1), dilution.: 1:50 B. Immunohistochemical analysis of paraffin- embedded hepatocellular carcinoma using anti-Phospho- Gab1(pY627) RabMAb(catalog #1128-1). C. Dot Blot analysis on immunogen phospho-peptide (A) a n d non-phospho peptide (B) uding anti-Phospho-Gab1 (pY627) RabMAb (catalog #1128-1), dilution 1:1,000. |
性状 | 【反应特异性】Human
【克隆 ID】E128 【用途】WB , IHC , IP 【抗原分子量】105 kDa |
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