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| 生化科研试剂 >> 抗体产品 >> 一抗 |
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Gab2 Rabbit Antibody
Rabbit Monoclonal IgG |
| 别 名： |
GRB2-associated binder 2, pp100 |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177822 |
Gab2 Rabbit Antibody |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human , Mouse , Rat
【克隆 ID】EP369Y
【用途】WB , ICC , FC , IP
【抗原分子量】97 kDa |
| 质量标准： |
【产品介绍】Gab2 (Grb2-associated binder-2) is an adapt
o r protein involved in numerous intracellular
signaling pathways via its interaction with recept
o r tyrosine kinases (RTKs), growth fact o r s
a n d cytokines. Gab2 is a substrate of various
RTKs, including EGFR, insulin recept o r , cytokine recept
o r s as well as B a n d T cell antigen recept o r s;
Gab2 acts as a docking protein f o r several
SH2-containing proteins (1-3). Upon tyrosine phosph
o r ylation, Gab2 interacts with SHP2 tyrosine phosphatase
a n d GRB2 adapt o r protein PI3-kinase, CrkL a n d
SHC (4-5).
WB: 1:500
ICC: 1:50
Flow Cytometry: 1:20
IP: 1:50
A. Western blot analysis of anti-Gab2 RabMAb
(cat. # 1631-1), dilution 1:500. A: K562 B: MCF-7
B. Immunoflu o r escent staining of PC-12 cells
using anti-Gab-2 RabMAb (cat. # 1631-1).
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