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生化科研试剂 >> 抗体产品 >> 一抗 |
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Gab2 Rabbit Antibody Rabbit Monoclonal IgG |
别 名: |
GRB2-associated binder 2, pp100 |
货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
1227177822 |
Gab2 Rabbit Antibody |
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100ul |
询价 |
现货 |
3天 |
提示信息:偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体,下单前请联系客服。 |
性 状: |
【反应特异性】Human , Mouse , Rat 【克隆 ID】EP369Y 【用途】WB , ICC , FC , IP 【抗原分子量】97 kDa |
质量标准: |
【产品介绍】Gab2 (Grb2-associated binder-2) is an adapt o r protein involved in numerous intracellular signaling pathways via its interaction with recept o r tyrosine kinases (RTKs), growth fact o r s a n d cytokines. Gab2 is a substrate of various RTKs, including EGFR, insulin recept o r , cytokine recept o r s as well as B a n d T cell antigen recept o r s; Gab2 acts as a docking protein f o r several SH2-containing proteins (1-3). Upon tyrosine phosph o r ylation, Gab2 interacts with SHP2 tyrosine phosphatase a n d GRB2 adapt o r protein PI3-kinase, CrkL a n d SHC (4-5). WB: 1:500 ICC: 1:50 Flow Cytometry: 1:20 IP: 1:50
A. Western blot analysis of anti-Gab2 RabMAb (cat. # 1631-1), dilution 1:500. A: K562 B: MCF-7
B. Immunoflu o r escent staining of PC-12 cells using anti-Gab-2 RabMAb (cat. # 1631-1).
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