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Gata1 (GATA1)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113618-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | GATA1 antibody, ERYF1 antibody, GATA-1 antibody, GF-1 antibody, GF1 antibody, NFE1 antibody, XLTT antibody, Erythroid transcription factor antibody, NF-E1 DNA-binding protein antibody |
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| 产品参数 | 【产品介绍】Gata1 is a transcription activator belonging
to the GATA family of transcription factors with importance in cell growth. Gata1 is a Cys2-Cys2 zinc finger DNA binding protein commonly found in erythroid red blood cells and megakaryotic platelet producing cells, and it is critical in the development process of both (1). It binds to the consensus sequence of [AT]GATA[AG] within regulatory regions of globin genes and genes in erythroid cells, leading to transcription of alpha spectrin structural protein necessary for the red blood cell's shape. In humans, GATA-1 can enhance the transcription rate up to 100 times (2). Mutations in Gata1 have been implicated to X-linked dyserythropoietic anemia, thrombocytopenia, Down's syndrome in children, congenital transient myeloproliferative syndrome, and acute megakaryocytic leukemia (2, 3). Recommended Applications WB Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) Molt-4, (B) TF-1, (C) K562, and (D) HL-60 cell lysates using anti-Gata1 RabMAb (cat. #5196-1). Specificity A synthetic peptide corresponding to residues in human Gata1 was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR2820(2) 【用途】WB 【抗原分子量】43kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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