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| 生化试剂 >> 抗体产品 >> 一抗 |
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Gata1 (GATA1)
Rabbit Monoclonal Antibody |
| 别 名： |
GATA1 antibody, ERYF1 antibody, GATA-1 antibody, GF-1 antibody, GF1 antibody, NFE1 antibody, XLTT antibody, Erythroid transcription factor antibody, NF-E1 DNA-binding protein antibody |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177824 |
Gata1 (GATA1) |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human
【克隆 ID】EPR2820(2)
【用途】WB
【抗原分子量】43kDa
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| 质量标准： |
【产品介绍】Gata1 is a transcription activator belonging
to the GATA family of transcription factors with
importance in cell growth. Gata1 is a Cys2-Cys2 zinc
finger DNA binding protein commonly found in erythroid
red blood cells and megakaryotic platelet producing
cells, and it is critical in the development process of
both (1). It binds to the consensus sequence of
[AT]GATA[AG] within regulatory regions of globin genes
and genes in erythroid cells, leading to transcription
of alpha spectrin structural protein necessary for the
red blood cell's shape. In humans, GATA-1 can enhance
the transcription rate up to 100 times (2). Mutations
in Gata1 have been implicated to X-linked
dyserythropoietic anemia, thrombocytopenia, Down's
syndrome in children, congenital transient myeloproliferative syndrome, and acute
megakaryocytic leukemia (2, 3).
Recommended Applications
WB
Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000
Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) Molt-4, (B) TF-1, (C) K562,
and (D) HL-60 cell lysates using anti-Gata1 RabMAb
(cat. #5196-1). Specificity A synthetic peptide corresponding to residues in human
Gata1 was used as an immunogen. |
| 贮 存： |
Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt |
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