GIPR

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 GIPR antibody, MGC126722 antibody, PGQTL2 antibody, Gastric inhibitory polypeptide receptor antibody, Glucose-dependent insulinotropic polypeptide receptor antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Gastric inhibitory polypeptide, also
called glucose-dependent insulinotropic polypeptide, is
a 42-amino acid polypeptide synthesized by K cells of
the duodenum and small intestine. It was
originally identified as an activity in gut extracts
that inhibited gastric acid secretion and gastrin
release, but subsequently was demonstrated to
stimulate insulin release potently in the presence
of elevated glucose. The insulinotropic effect on
pancreatic islet beta-cells was then recognized to be
the principal physiologic action of GIPR. Together
with glucagon-like peptide-1, GIPR is largely
responsible for the secretion of insulin after eating. It
is involved in several other facets of the anabolic
response (1).


Recommended Applications

WB, IHC, ICC, FC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:50 - 100
ICC: 1:50 - 100
FC: 1:10 - 100
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) BxPC-3 and (B) fetal
heart lysates using anti-GIPR RabMAb (cat. #5300-1).

Immunohistochemical analysis of paraffin-embedded
human pancreas tissue using anti-GIPR RabMAb (cat.# 5300-1).

Specificity

A synthetic peptide corresponding to residues on
the C-terminus in human GIPR was used as an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR5827
【用途】WB , IHC , ICC , FC
【抗原分子量】55kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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