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Gelsolin Rabbit Antibody
英文名：Rabbit Monoclonal IgG
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113625-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | Actin-depolymerizing fact o r , ADF, Brevin, AGEL |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | 【产品介绍】Gelsolin is a large a n d complex
actin-binding protein that belongs to actin-severing gelsolin/villin super family. Gelsolin is a regulat o r of actin filament assembly a n d disassembly a n d consists of six homologous subdomains (S1-S6). When C-terminal tail (S6) is bound to calcium ion, it straightens a n d exposes actin binding sites located on S2s helices, leading to Gelsolin actin-serving activity (1). Gelsolin is inhibited by phosphatidylinositol (4,5)-bisphosphate (PIP2), where PIP2 will bind to S1, S2, a n d S3 sites. Gelsolin is involved in podosome f o r mation a n d has been linked to inhibition of apoptosis by preventing release of cytochrome C (2). WB: 1:1000 5000 IHC: 1:100-250 A. Western blot analysis on NIH 3T3 cell lysate using anti-Gelsolin RabMAb (cat. #2097-1), 1:5000 dilution. B. Immunohistochemical analysis of paraffin-embedded human tonsils using anti-Gelsolin RabMAb (cat# 2097-1) |
| 性状 | 【反应特异性】Human
【克隆 ID】EP1940Y 【用途】WB , IHC 【抗原分子量】90 kDa |
| 贮存 |
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