GFAP (C-term)

英文名:Rabbit Monoclonal IgG
Cas号:
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别 名 GFAP
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Glial fibrillary acidic protein (GFAP)
belongs to the class III of the intermediate filament
(IF) proteins highly specific to astrocytes which
function as nerve cells in the brain a n d in the
central nervous system (CNS) (1-2). Two other class III
IF proteins, nestin a n d vimentin, dominate in
immature astrocytes, while GFAP is most abundant in
mature astrocytes (3). GFAP is used as a marker
to distinguish astrocytes f o r m other glial cells
during development. Mutations in GFAP cause Alex a n d
er disease, a rare dis o r der of the CNS. Most
frequent mutations are located at Arginine 79 o r 239 (4).


Recommended Applications

WB, IHC, IP
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:250-500
IP: 1:50
Species Reactivity *

Human, Rat

*Cross reactivity determined by western blot only.


Products Data


A. Western blot analysis on Rat brain lysate using
anti-GFAP (C-term) RabMAb (cat. # 1665-1).

B. Immunohistochemical analysis of paraffin-embedded
human brain using anti-GFAP (C-term) RabMAb (cat. # 1665-1).


Specificity

A synthetic peptide corresponding to residues in the
C-term of human GFAP was used as immunogen.
性状 【反应特异性】Human , Rat
【克隆 ID】EP672Y
【用途】WB , IHC , IP
【抗原分子量】50 kDa
贮存 Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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