HER3 / ErbB3 Phospho (pY1222) (ERBB3)

英文名:HER3 / ErbB3 Phospho (pY1222) (ERBB3)
Cas号:
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别 名 ERBB3 antibody, ErbB-3 antibody, HER3 antibody, LCCS2 antibody, MDA-BF-1 antibody, MGC88033 antibody, c-erbB-3 antibody, c-erbB3 antibody, erbB3-S antibody, p180-ErbB3 antibody, p45-sErbB3 antibody, p85-sErbB3 antibody, Receptor tyrosine-protein kinase er
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】HER3 / ErbB3 is a member of the
ErbB/EGF receptor protein tyrosine kinase family
(1,2). Tyrosine phosphorylation of HER3/ErbB3 depends on
its association with other ErbB tyrosine kinases
(3). Phosphorylation sites in the carboxy-terminal
tail mediate downstream signaling pathways. HER3 / ErbB3
is highly expressed in many cancer cells, and it may
work together with other Erb members in tumorigenesis
and proliferation (4, 5).

Recommended Applications
WB, ICC, IP
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
ICC: 1:50 - 100
IP: 1:10 - 100
Species Reactivity *
Human
*Species cross-reactivity is based on WB analysis
Products Data

Western blot analysis on SKBR-3 cell lysates
using anti-Phospho-HER3 / ErbB3 (pY1222) RabMAb
(cat. #3871-1). Cells were either (A) untreated (B)
treated with Neuregulin.

Specificity
A phospho specific peptide corresponding to
residues surrounding Tyrosine 1222 of human HER3 / ErbB3
was used as an immunogen. This antibody only detects
HER3 / ErbB3 phosphorylated at Tyrosine 1222.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR5807
【用途】WB , ICC , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】185kDa
贮存 Store at -20° C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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