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HIAP-1/BIR3
英文名：HIAP-1/BIR3
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114392-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | Inhibit o r of apoptosis protein 1, HIAP1, HIAP-1, C-IAP2, TNFR2-TRAF-signaling complex protein 1, IAP homolog C, Apoptosis inhibit o r 2, API2, RING finger protein 49 |
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| 产品参数 | 【产品介绍】cIAP-2, also known as HIAP-1, is a member of
the inhibit o r of apoptosis (IAP) family of proteins. These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus (1). cIAP-2 is localized to the cytoplasm. The BIR motifs region interacts with TNF recept o r associated fact o r s 1 a n d 2 (TRAF1 a n d TRAF2) to f o r m a heteromeric complex, which is then recruited to the tum o r necrosis fact o r recept o r 2 (TNFR2). This complex is thought to play a role in inhibition of apoptosis (2,3). cIAP-2 inhibits cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade a n d apoptosis (4). WB: 1:500 IHC: 1:50 ICC: 1:100 IP: 1:50 A. Western blot analysis on Daudi cell lysate using anti-HIAP-1/BIR3 RabMAb (catalog #1040-1), dilution 1:1,000. B. Immunohistochemical analysis of human n o r mal spleen using anti-HIAP-1/BIR3 RabMAb (catalog #1040-1). |
| 性状 | 【产品类型】Rabbit Monoclonal IgG
【反应特异性】Human , Rat 【克隆 ID】E40 【用途】WB , IHC , ICC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】72 kDa |
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