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HTR2C
英文名:HTR2C
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308114420-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | HTR2C antibody, 5-HT2C antibody, 5-HTR2C antibody, HTR1C antibody, 5-hydroxytryptamine receptor 2C antibody, Serotonin receptor 2C antibody |
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产品参数 | 【产品介绍】Serotonin (5-hydroxytryptamine, 5-HT),
a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. HTR2C is the 2C subtype of serotonin receptor. Its isoforms differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in HTR2C in depressed suicide victims (1). Recommended Applications WB Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) SH-SY5Y, (B) A431, and (C) BxPC-3 cell lysates using anti-HTR2C RabMAb (cat. #5273-1). Specificity A synthetic peptide corresponding to residues in human HTR2C was used as an immunogen. |
性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human 【克隆 ID】EPR6486 【用途】WB 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】60kDa |
贮存 | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |