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Human IgD (IGHD)
英文名:Human IgD (IGHD)
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308114423-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | IGHD antibody, FLJ00382 antibody, FLJ46727 antibody, MGC29633 antibody, Ig delta chain C region antibody, antibody |
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产品参数 | 【产品介绍】Immunoglobulin (Ig) molecules consist of
two chains, one heavy chain and one light chain, each consisting of a variable and a constant region. An IgD molecule contains thus a delta heavy chain combined with either a kappa or lambda light chain. It is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM (1). Secreted IgD might enhance immune protection by regulating B cell homeostasis and activation (2). After the antigen binds to the B-cell receptor, secreted IgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD (1). Recommended Applications WB, IHC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:1,000 - 2,000 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on human tonsil lysate using anti-Human IgD (IGHD) RabMAb (cat. #5231-1). Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Human IgD (IGHD) RabMAb (cat. #5231-1). Specificity A synthetic peptide corresponding to residues in human IgD (IGHD) was used as an immunogen. |
性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human 【克隆 ID】EPR6146 【用途】WB , IHC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】75kDa |
贮存 | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |