ICAM-1 DyLight® 488

英文名:ICAM1
Cas号:
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别 名 ICAM1 antibody, BB2 antibody, CD54 antibody, P3.58 antibody, Intercellular adhesion molecule 1 antibody, Major group rhinovirus receptor antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Antigen-specific cell contacts in the
immune system are strengthened by antigen-
nonspecific interactions, mediated in part by
lymphocyte-function associated (LFA) antigens.
ICAM-1 (intercellular adhesion molecule-1) has been
defined as a ligand for LFA-1. Monoclonal antibodies
to ICAM-1 block T lymphocyte adhesion to fibroblasts
and endothelial cells; they disrupt the interaction
between cytotoxic T cells and target cells (1). The
normal function of human intercellular adhesion
molecule-1 (ICAM-1) is to provide adhesion
between endothelial cells and leukocytes after injury
or stress. However, ICAM-1 is also used as a receptor by
the major group of human rhinoviruses and is a catalyst
for the subsequent viral uncoating during cell entry
(2). ICAM-1 is found on leukocytes, fibroblasts,
epithelial cells and endothelial cells; its expression
is regulated by inflammatory cytokines (1).

Recommended Applications
FC
Applications and Recommended Dilution Factors
FC: 1:100
Species Reactivity
Human
Products Data

Flow cytometric analysis of Ramos cells using ICAM-1
RabMAb (DyLight® 488 conjugate, cat.# 4589-1) (red)
compared to a nonspecific negative control antibody (green).

Specificity
A recombinant protein corresponding to a fragment near
the C-terminus of human ICAM-1 was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR4776
【用途】FC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】89kDa
贮存 Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt.
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