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生化科研试剂 >> 抗体产品 >> 一抗 |
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ICAM-1 DyLight® 488 ICAM1 |
别 名: |
ICAM1 antibody, BB2 antibody, CD54 antibody, P3.58 antibody, Intercellular adhesion molecule 1 antibody, Major group rhinovirus receptor antibody |
货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
1227178977 |
ICAM-1 DyLight® 488 |
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100ul |
询价 |
现货 |
3天 |
提示信息:偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体,下单前请联系客服。 |
性 状: |
【产品类型】Rabbit Monoclonal Antibody 【反应特异性】Human 【克隆 ID】EPR4776 【用途】FC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】89kDa |
质量标准: |
【产品介绍】Antigen-specific cell contacts in the immune system are strengthened by antigen- nonspecific interactions, mediated in part by lymphocyte-function associated (LFA) antigens. ICAM-1 (intercellular adhesion molecule-1) has been defined as a ligand for LFA-1. Monoclonal antibodies to ICAM-1 block T lymphocyte adhesion to fibroblasts and endothelial cells; they disrupt the interaction between cytotoxic T cells and target cells (1). The normal function of human intercellular adhesion molecule-1 (ICAM-1) is to provide adhesion between endothelial cells and leukocytes after injury or stress. However, ICAM-1 is also used as a receptor by the major group of human rhinoviruses and is a catalyst for the subsequent viral uncoating during cell entry (2). ICAM-1 is found on leukocytes, fibroblasts, epithelial cells and endothelial cells; its expression is regulated by inflammatory cytokines (1).Recommended Applications FC Applications and Recommended Dilution Factors FC: 1:100 Species Reactivity Human Products Data Flow cytometric analysis of Ramos cells using ICAM-1 RabMAb (DyLight® 488 conjugate, cat.# 4589-1) (red) compared to a nonspecific negative control antibody (green). Specificity A recombinant protein corresponding to a fragment near the C-terminus of human ICAM-1 was used as an immunogen. |
贮 存: |
Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt. |
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