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ICAM-1 DyLight® 488
英文名:ICAM1
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308114427-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | ICAM1 antibody, BB2 antibody, CD54 antibody, P3.58 antibody, Intercellular adhesion molecule 1 antibody, Major group rhinovirus receptor antibody |
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产品参数 | 【产品介绍】Antigen-specific cell contacts in the
immune system are strengthened by antigen- nonspecific interactions, mediated in part by lymphocyte-function associated (LFA) antigens. ICAM-1 (intercellular adhesion molecule-1) has been defined as a ligand for LFA-1. Monoclonal antibodies to ICAM-1 block T lymphocyte adhesion to fibroblasts and endothelial cells; they disrupt the interaction between cytotoxic T cells and target cells (1). The normal function of human intercellular adhesion molecule-1 (ICAM-1) is to provide adhesion between endothelial cells and leukocytes after injury or stress. However, ICAM-1 is also used as a receptor by the major group of human rhinoviruses and is a catalyst for the subsequent viral uncoating during cell entry (2). ICAM-1 is found on leukocytes, fibroblasts, epithelial cells and endothelial cells; its expression is regulated by inflammatory cytokines (1). Recommended Applications FC Applications and Recommended Dilution Factors FC: 1:100 Species Reactivity Human Products Data Flow cytometric analysis of Ramos cells using ICAM-1 RabMAb (DyLight® 488 conjugate, cat.# 4589-1) (red) compared to a nonspecific negative control antibody (green). Specificity A recombinant protein corresponding to a fragment near the C-terminus of human ICAM-1 was used as an immunogen. |
性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human 【克隆 ID】EPR4776 【用途】FC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】89kDa |
贮存 | Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt. |