IRF-4

英文名:IRF4
Cas号:
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别 名 IRF4 antibody, LSIRF antibody, MUM1 antibody, Interferon regulatory factor 4 antibody, Multiple myeloma oncogene 1 antibody, NF-EM5 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】IRF-4 belongs to the IRF (interferon
regulatory factor) family of transcription
factors, characterized by an unique tryptophan pentad
repeat DNA-binding domain. The IRFs are important in
the regulation of interferons in response to infection
by viruses and the regulation of interferon-
inducible proteins.IRF-4 is lymphocyte specific
and negatively regulates Toll-like-receptor (TLR)
signaling that is central to the activation of innate
and adaptive immune systems. A mutation in IRF-4 may be
a cause of multiple myeloma (1).

Recommended Applications
WB, IHC, IP
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
IP: 1:10 - 100
Species Reactivity *
Human
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) Ramos, (B) HuT-78, and (C)
IM-9 cell lysates using anti-IRF-4 RabMAb (cat. #5184-1).

Immunohistochemical analysis of paraffin-embedded
human colon tissue using anti-IRF-4 RabMAb (cat. #5184-1).

Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti-IRF-4 RabMAb (cat. #5184-1).

Specificity
A synthetic peptide corresponding to residues on
the N-terminus in human IRF-4 was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR5653
【用途】WB , IHC , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】51kDa
贮存 Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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