KLK2

英文名:KLK2
Cas号:
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别 名 KLK2 antibody, KLK2A2 antibody, MGC12201 antibody, hK2 antibody, Kallikrein-2 antibody, Tissue kallikrein-2 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】KLK2 is a serine protease produced by
secretory epithelial cells in the prostate (1). It is
a glandular kallikrein that cleaves Met-Lys and
Arg-Ser bonds in kininogen to release Lys-bradykinin
(2). KLK2 can activate the proforms of PSA
(prostate-specific antigen) and urokinase type
plasminogen activator and inactivate plasminogen
activator inhibitor-1, suggesting a possible role in
a proteolytic cascade associated with prostate cancer.
Thus, it may promote tumor growth, and metastasis
and inhibition of KLK2 activity may, therefore, slow
down tumor spread (1).

Recommended Applications
WB, ICC
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
ICC: 1:50 - 100
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) LnCaP, (B) Molt-4, (C)
human seminoma, and (D) PC-3 lysates using anti-KLK2
RabMAb (cat. #5341-1).

Specificity
A synthetic peptide corresponding to residues in human
KLK2 was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6676
【用途】WB , ICC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】33kDa
贮存 Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用。
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