1. 首页
  2. 生化科研试剂
  3. 抗体产品
  4. 一抗

LAT Phospho (pY191)

英文名：LAT Phospho (pY191)
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308114486-100ul 现货 0 ￥0
- +
偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。
别 名 36 kDa phospho-tyrosine adapter protein, pp36, p36-38
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】LAT (linker f o r activation of T-cells)
is involved in the T-cell antigen recept o r (TCR)
signal transduction pathway, a n d may play an imp o r
tant role downstream in activating protein tyrosine
kinases (1). LAT is phosph o r ylated by ZAP-70/Syk
protein tyrosine kinases leading to recruitment of
multiple signaling molecules (2). It has been found
that Tyr191 a n d Tyr171 are required f o r
T-cell activation a n d Tyr132 is required f o r
the activation of PLCgamma1 a n d Ras signaling
pathways, respectively. Tyr226 a n d Tyr191 are required
f o r Vav binding, whereas Tyr171 a n d Tyr132 are
necessary f o r association a n d activation
of phosphoinositide 3-kinase activity a n d PLCgamma1 (3).

WB: 1:2,000
IHC: 1:50
ICC: 1:50
IP: 1:10

A. Western blot analysis on Jurkat cell lysate
using anti-Phospho-LAT (pY191) RabMAb
(cat. #1225-1); dilution 1:2,000. (1) Jurkat plus anti-CDC
a n d (2) Jurkat negative control.

B. Immunohistochemical analysis of paraffin-embedded
human tonsils using anti-Phospho-LAT (pY191) RabMAb
(cat. #1225-1).
性状 【产品类型】Rabbit Monoclonal IgG
【反应特异性】Human , Mouse , Rat
【克隆 ID】E225
【用途】WB , IHC , ICC , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】36/38 kDa
贮存
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。