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Ku80 (XRCC5)
英文名：Ku80 (XRCC5)
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114483-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | XRCC5 antibody, FLJ39089 antibody, KARP-1 antibody, KARP1 antibody, KU80 antibody, KUB2 antibody, Ku86 antibody, NFIV antibody, X-ray repair cross-complementing protein 5 antibody, X-ray repair complementing defective repair in Chinese hamster cells 5 (do |
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| 产品参数 | 【产品介绍】The Ku antigen is a DNA-associated
nuclear protein originally recognized by the sera of patients with autoimmune diseases (1). It plays a key role in multiple nuclear processes, such as DNA repair, chromosome maintenance, transcription regulation, and V(D)J recombination (2). The Ku protein is composed of 70 and 80 kDa subunits (Ku70 and Ku80, respectively) and contributes to genomic integrity through its ability to bind DNA double-strand breaks and facilitate repair by the non-homologous end-joining pathway (3). When bound to DNA, the Ku 70/80 heterodimer enhances the kinase activity of the catalytic subunit of the DNA-dependent protein kinase, DNA-PKcs (4). Recommended Applications WB, IHC, ICC, IP Applications and Recommended Dilution Factors WB: 1:10,000 - 20,000 IHC: 1:250 - 500 ICC: 1:500 - 1000 IP: 1:50 Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on (A) A549 treated with FBS (B) HeLa (C) HepG2 (D) MCF-7 cell lysates using anti-Ku80 RabMAb (cat. #2620-1), dilution 1:50,000. B. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Ku80 RabMAb (cat.# 2620-1). C. Immunofluorescent staining of HeLa cells using anti-Ku80 RabMAb (cat. #2620-1). Specificity A synthetic peptide corresponding to residues in human Ku80 was used as an immunogen. |
| 性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human 【克隆 ID】EPR3468 【用途】WB , IHC , ICC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】86kDa |
| 贮存 | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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