LMAN1

英文名:LMAN1
Cas号:
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别 名 LMAN1 antibody, ERGIC-53 antibody, ERGIC53 antibody, F5F8D antibody, FMFD1 antibody, MCFD1 antibody, MR60 antibody, gp58 antibody, Protein ERGIC-53 antibody, ER-Golgi intermediate compartment 53 kDa protein antibody, Gp58 antibody, Intracellular mannose-s
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】LMAN1 is a type I integral membrane
protein localized in the intermediate region between
the endoplasmic reticulum and the Golgi,
presumably recycling between the two compartments. It is
a mannose-specific lectin and is a member of a novel
family of plant lectin homologs in the secretory pathway
of animal cells. Mutations in LMAN1 are associated with
a coagulation defect. Using positional cloning, it
was identified to lead to combined factor V-factor
VIII deficiency, a rare, autosomal recessive disorder
in which both coagulation factors V and VIII are
diminished (1).

Recommended Applications
WB, IHC, ICC
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:50 - 100
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) HeLa, (B) 293T, (C)
SH-SY5Y, (D) NCI-H460, (E) Jurkat, and (F) JAR cell
lysates using anti-LMAN1 RabMAb (cat. #5406-1).

Immunohistochemical analysis of paraffin-embedded
human kidney tissue using anti-LMAN1 RabMAb (cat. #5406-1).

Immunohistochemical analysis of paraffin-embedded
human papillary carcinoma of thyroid gland tissue
using anti-LMAN1 RabMAb (cat. #5406-1).

Specificity
A synthetic peptide corresponding to residues in human
LMAN1 was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6979
【用途】WB , IHC , ICC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】53kDa
贮存 Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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