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LIN28A DyLight® 488
英文名:LIN28A DyLight® 488
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308114496-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | LIN28A antibody, CSDD1 antibody, FLJ12457 antibody, LIN-28 antibody, LIN28 antibody, ZCCHC1 antibody, Protein lin-28 homolog A antibody, Zinc finger CCHC domain-containing protein 1 antibody |
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产品参数 | 【产品介绍】LIN28A, a promoter of pluripotency, is
a developmentally regulated RNA binding protein, which selectively blocks the processing of pri-let-7 miRNAs in embryonic cells (1,2). One of the let-7 family members, let-7g targets and represses LIN28 through four 3'-UTR binding sites. It has been reported that LIN28/let-7 pair has the potential to act as a 'toggle switch' that balances the decision to maintain pluripotency vs. differentiation (3). LIN28 was identified as a negative regulator of miRNA biogenesis and suggested that it may play a central role in blocking miRNA-mediated differentiation in stem cells and in certain cancers (1). Recommended Applications ICC, FC Applications and Recommended Dilution Factors ICC: 1:50 - 100 FC: 1:100 Species Reactivity Human Products Data Immunofluorescent staining of NCCIT cells using anti-LIN28A antibody conjugated with Dylight 488 (green, Cat# 4584-1) and Dapi (blue). Flow cytometric analysis of NCCIT cells using LIN28A RabMAb (DyLight® 488 conjugate, cat.# 4584-1) (red) compared to a nonspecific negative control antibody (green). Specificity A synthetic peptide corresponding to residues in human LIN28A was used as an immunogen. |
性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human 【克隆 ID】EPR4640 【用途】ICC , FC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】26kDa |
贮存 | Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt. |