Recombinant Human Fms-related Tyrosine Kinase 3 Ligand (CHO-expressed)

英文名:
Cas号:
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Fms-related Tyrosine Kinase 3 Ligand (CHO-expressed) 是一种细胞因子,能够促进造血干细胞及其祖细胞的再生和分化。
Synonyms
rHuFlt-3 Ligand; Flt3 ligand; FL; SL cytokine; Flt-3L ; 重组人 Fms 样酪氨酸激酶 3 配体 (CHO 细胞表达)
Species
Human

Source
CHO

Accession
P49771

Gene ID
2323

Molecular Weight
18-22 kDa

AA Sequence
TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA

Biological Activity
The ED50 is <1 ng/mL as measured by human AML5 cells, corresponding to a specific activity of >1 × 106 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Fms-related Tyrosine Kinase 3 Ligand (CHO-expressed) (rHuFlt-3 Ligand) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Human Fms-related Tyrosine Kinase 3 Ligand (CHO-expressed) (rHuFlt-3 Ligand) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Fms-related tyrosine kinase 3 ligand is a type of cell factor, able to promote the generation and differentiation of hematopoietic stem cells and their progenitor cells. The mRNA of Fms-related tyrosine kinase 3 ligand is highly expressed in certain tissues, including peripheral blood mononuclear cells, the heart, placenta, lung, spleen and thymus tissue, and is also expressed to a certain extent in non-hematopoietic tissues, including the prostate, testis, ovaries, intestines, liver, kidney and skeletal muscle[1].
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