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Recombinant Mouse Beta Defensin-2
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| 性状 | Recombinant Mouse Beta Defensin-2 是一种参与对抗微生物入侵反应的抗微生物肽。
Synonyms rMuBD-2; DEFB2 ; 重组小鼠 β-防御素-2 Species Mouse Source E. coli Accession P82020 Gene ID 13215 Molecular Weight Approximately 5.5 kDa AA Sequence AVGSLKSIGY EAELDHCHTN GGYCVRAICP PSARRPGSCF PEKNPCCKYM K Biological Activity Full biological activity determined by a chemotaxis bioassay using immature human dendritic cells is in a concentration of 10-100 ng/ml. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse Beta Defensin-2 (rMuBD-2) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Mouse Beta Defensin-2 (rMuBD-2) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Mouse Beta Defensin-2 (mBD2) is produced by mouse urothelium in response to intravesicular BCG as a defense mechanism against BCG, and blocking mBD2 by an anti-mBD2 antibody increased the effectiveness of BCG[1]. |
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