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Recombinant Mouse DKK-1 (CHO-expressed)
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性状 | Recombinant Mouse DKK-1 (CHO-expressed) 是 Wnt信号通路的有效抑制剂,是dickkopf 家族成员之一。
Synonyms rMuDKK-1; mDkk-1; Dickkopf-1 ; 重组小鼠 DKK-1 (CHO细胞表达) Species Mouse Source CHO Accession O54908 Gene ID 13380 Molecular Weight 19-20 kDa AA Sequence SATLNSVLIN SNAIKNLPPP LGGAGGQPGS AVSVAPGVLY EGGNKYQTLD NYQPYPCAED EECGSDEYCS SPSRGAAGVG GVQICLACRK RRKRCMRHAM CCPGNYCKNG ICMPSDHSHF PRGEIEESII ENLGNDHNAA AGDGYPRRTT LTSKIYHTKG QEGSVCLRSS DCAAGLCCAR HFWSKICKPV LKEGQVCTKH KRKGSHGLEI FQRCYCGEGL ACRIQKDHHQ AS Biological Activity The ED50 is <6 μg/mL as measured in stimulation of alkaline phosphatase activity using CCl-226 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse DKK-1 (CHO-expressed) (rMuDKK-1) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Mouse DKK-1 (CHO-expressed) (rMuDKK-1) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Mature mouse Dkk-1 is a 40 kDa glycosylated protein that shares 86%, 96%, 83% and 82% amino acid (aa) sequence identity with human, rat, rabbit and bovine Dkk-1, respectively. It also shares 41% and 36% aa identity with human Dkk-2 and Dkk-4, respectively[1]. Dkk1 is a secreted Wnt inhibitor and member of a distinct multigene family, this inhibition plays a key role in heart, head and forelimb development during anterior morphogenesis of the embryo[2][3]. |
贮存 |
- Recombinant Rat Ciliary Neurotrophic Factor
- Recombinant Human Cardiotrophin-1
- Recombinant Mouse CXCL16
- Recombinant Mouse CXCL3
- Recombinant Mouse DKK-1 (CHO-expressed)
- Recombinant Human Dickkopf Related Protein-1 (HEK293-expressed)
- Recombinant Human Epithelial Neutrophil Activating Peptide-78/CXCL5 (HEK293-expressed)
- Recombinant Human Epithelial Neutrophil Activating Peptide-78/CXCL5
- Recombinant Human Eotaxin/CCL11