本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
Recombinant Human Eotaxin-3/CCL26
| 别 名 | |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | |
| 性状 | Recombinant Human Eotaxin-3/CCL26 通过CCR3受体发挥作用，是嗜酸性粒细胞选择性化学诱导剂的活性。
Synonyms rHuEotaxin-3/CCL26; C-C motif chemokine 26; MIP-4-alpha; TSC-1; SCYA26 ; 重组人嗜酸性细胞趋化因子 (CCL26) Species Human Source E. coli Accession Q9Y258 Gene ID 10344 Molecular Weight Approximately 8.4 kDa AA Sequence TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L Biological Activity Full biological activity determined by a chemotaxis bioassay using human CCR3 transfected HEK293 cells is in a concentration range of 0.5-2.0 μg/ml. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Eotaxin-3/CCL26 (rHuEotaxin-3/CCL26) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Human Eotaxin-3/CCL26 (rHuEotaxin-3/CCL26) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Eotaxin-3 (CCL26) is a CC chemokine that signals exclusively via the CCR3 receptor and has eosinophil-selective chemoattractant activity. Comparison of Eotaxin-1 (CCL11) and Eotaxin-2 (CCL24), demonstrates differences in their expression profiles, cell specificity and effector kinetics, implying distinct biological actions[1]. Human CCL26 plays a role in the sustained inflammation observed in patients with severe eosinophilic asthma and reveal CCL26 as a potential target for treating patients with eosinophilic asthma that are refractory to classic therapies[2]. |
| 贮存 |
沪公网安备 31012002003054号