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Recombinant Mouse Eotaxin/CCL11
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性状 | Recombinant Mouse Eotaxin/CCL11是嗜酸性粒细胞、嗜碱性粒细胞和Th2淋巴细胞的有效化学诱导剂。
Synonyms rMuEotaxin/CCL11; C-C motif chemokine 11; Eosinophil chemotactic protein; SCYA11 ; 重组小鼠嗜酸粒细胞趋化因子 (CCL11) Species Mouse Source E. coli Accession P48298 Gene ID 20292 Molecular Weight Approximately 8.4 kDa AA Sequence HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP Biological Activity Full biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 100-1000 ng/ml. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse Eotaxin/CCL11 (rMuEotaxin/CCL11) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Mouse Eotaxin/CCL11 (rMuEotaxin/CCL11) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CCL11 is a small cytokine belonging to the CC chemokine family. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergicresponses[1]. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. CCL11 is a potent chemoattractant for eosinophils, basophils, and Th2 lymphocytes. CCL11 has a number of important biological functions in disease processes. It plays a critical role in allergic and nonallergic inflammatory reactions, such as mycobacterial and schistosomal induced granulomatosis[2]. |
贮存 |
- Recombinant Human Dickkopf Related Protein-1 (HEK293-expressed)
- Recombinant Human Epithelial Neutrophil Activating Peptide-78/CXCL5 (HEK293-expressed)
- Recombinant Human Epithelial Neutrophil Activating Peptide-78/CXCL5
- Recombinant Human Eotaxin/CCL11
- Recombinant Mouse Eotaxin/CCL11
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- Recombinant Rat Eotaxin-2/CCL24
- Recombinant Human Eotaxin-3/CCL26
- Recombinant Human Erythropoietin (CHO-expressed)